ADIPOSE TISSUE OF THE GREATER OMENTUM: MORPHOLOGY AND FUNCTION

  2. 2023
  3. ADIPOSE TISSUE OF THE GREATER OMENTUM: MORPHOLOGY AND FUNCTION

Kosharnyi V. V., Lysachenko O. D., Fylenko B. M., Roiko N. V., Konovalenko S. O.

ADIPOSE TISSUE OF THE GREATER OMENTUM: MORPHOLOGY AND FUNCTION

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About the author:

Kosharnyi V. V., Lysachenko O. D., Fylenko B. M., Roiko N. V., Konovalenko S. O.

Heading:

LITERATURE REVIEWS

Type of article:

Scientific article

Annotation:

Despite the fact that more and more publications about the structure and function of adipose tissue have recently appeared, further research may provide new insights into its role in metabolic diseases. Molecular and cellular mechanisms that regulate the functional activity of adipocytes, the issue of the interaction of adipose tissue with other structures of the body, as well as the role and significance of biologically active substances produced by adipocytes require in-depth research. The greater omentum, in which visceral fat accumulates and is a derivative of the peritoneum, was previously considered an inert adipose tissue, but this organ performs a large number of functions, including endocrine. White adipose tissue is an important endocrine organ that produces hormones and biologically active substances called adipokines and regulates many physiological processes. In this review, we focus on the omentum, the visceral white adipose tissue depot, as an adipocyte-rich organ. The article highlights the latest data on the morpho-functional features of the greater omentum as an endocrine organ and their significance in the development of obesity and type 2 diabetes. Changes in the greater omentum in obesity and their relationship with this disease are also described. Morphological changes in the greater omentum indicate that ischemia also plays an important role in the development of adipose tissue dysfunction in obesity.

Tags:

adipose tissue, diabetes, endocrine function, greater omentum, obesity, white adipocytes

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 52-56 pages, index UDC 616.382:616.53

DOI:

10.29254/2077-4214-2023-3-170-52-56

2023 Issue 3, 170
adipose tissue diabetes endocrine function greater omentum obesity white adipocytes
01.10.2023
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