Todurov I. M., Plehutsa O. I., Trots A. V., Hrynevych A. A., Kyryk V. O.
FEATURES OF THE MORBID BACKGROUND OF PATIENTS WITH SURGICAL PATHOLOGY OF ABDOMINAL CAVITY AND ACCOMPANYING METABOLIC SYNDROME
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About the author:
Todurov I. M., Plehutsa O. I., Trots A. V., Hrynevych A. A., Kyryk V. O.
Heading:
CLINICAL AND EXPERIMENTAL MEDICINE
Type of article:
Scientific article
Annotation:
Metabolic syndrome is a clinicopathological condition whose prevalence continues to increase, including among surgical patients. The spectrum of influence of the components of this syndrome on the development of various chronic diseases encourages ongoing research in terms of its impact on the morbid background and the formation of a vector of new approaches to prevention and treatment. The aim was to determine the morbid background and features of the metabolic syndrome in patients with surgical pathology of the abdominal cavity. The study included 1373 patients (796 of whom had metabolic syndrome) who underwent abdominal surgery between 2017 and 2022. The patients with metabolic syndrome group was divided into three main subgroups: a general surgical group, a bariatric group, and a group of cancer patients. In each group, the average values of patients' age, body mass index, and hospital stay were given, the most frequently performed surgical interventions were given in numerical terms, the percentage distribution of patients by gender was performed, and the components of concomitant pathology were described, which allowed for a clear statistical analysis of the morbid background. MS is a component that can lead to health problems and provoke the occurrence of many pathological conditions, including cardiovascular, respiratory, nervous, and endocrine systems. Based on the analysis of many studies and data from our centre, we can conclude that timely and mandatory diagnostic screening of metabolic disorders is important and that, if possible, correction or treatment of certain pathological conditions is necessary to improve the results of treatment of the underlying disease.
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Bibliography:
- Saklayen MG. The Global Epidemic of the Metabolic Syndrome. Curr Hypertens Rep. 2018 Feb 26;20(2):12. DOI: 10.1007/s11906-018- 0812-z.
- Tatarchuk TF, Tutchenko TM, Perekhrestenko OV, Kalashnikov OO, Hlamazda MI. Metabolic syndrome: what changed during last 30 years?. Reproductive Endocrinology. 2018;43:15-27. DOI: https://doi.org/10.18370/2309-4117 .2018. 43.15-27.
- Tzimas P, Petrou A, Laou E, Milionis H, Mikhailidis DP, Papadopoulos G. Impact of metabolic syndrome in surgical patients: should we bother? Br J Anaesth. 2015 Aug;115(2):194-202. DOI: 10.1093/bja/aev199.
- Turkoglu C, Duman BS, Gunay D, Cagatay P, Ozcan R, Buyukdevrim AS. Effect of abdominal obesity on insulin resistance and the components of the metabolic syndrome:evidence supporting obesity as the central feature. Obes Surg. 2003;13:699-705.
- Cullen A, Ferguson A. Perioperative management of the severely obese patient: a selective pathophysiological review. Can J Anaesth 2012;59:974-96.
- Bhayani NH, Hyder O, Frederick W, Schulick RD, Wolgang CL, Hirose K, et al. Effect of metabolic syndrome on perioperative outcomes after liver surgery: A National Surgical Quality Improvement Program (NSQIP) analysis. Surgery. 2012 Aug;152(2):218-26. DOI: 10.1016/j. surg.2012.05.037.
- Lopez-Nava G, Galvão MP, da Bautista-Castaño I, Jimenez A, De Grado T, Fernandez-Corbelle JP. Endoscopic sleeve gastroplasty for the treatment of obesity. Endoscopy. 2015 May;47(5):449-52. DOI: 10.1055/s-0034-1390766.
- Todurov IM, Mankovskyi BM, Saienko YA, Perekhrestenko OV, Plehutsa OI, Baka OM, et al. Metabolichna khirurhiia v likuvanni ozhyrinnia. Diabet. Ozhyrinnia. Metabolichnyi Syndrom». 2021;2(10):39-46. [in Ukrainian].
- Cordero P, Li J, Oben JA. Bariatric surgery as a treatment for metabolic syndrome. J R Coll Physicians Edinb. 2017 Dec;47(4):364-368. DOI: 10.4997/JRCPE.2017.414.
- Manahan MA, Shermak MA. Massive panniculectomy after massive weight loss. Plast Reconstr Surg. 2006;117(7):2191-2197; discussion 2198-2199.
- Arthurs ZM, Cuadrado D, Sohn V, Wolcott K, Lesperance K, Carter P, et al. Post-bariatric panniculectomy: pre-panniculectomy body mass index impacts the complication profile. Am J Surg. 2007 May;193(5):567-70; discussion 570. DOI: 10.1016/j.amjsurg.2007.01.006.
- Payer JJr, Ziak P, Fedeles JJr, Brazdilova K, Fedeles J. Changes in metabolic syndrome parameters after liposuction. Bratisl Lek Listy. 2013;114(6):349-52. DOI: 10.4149/bll_2013_075.
- Zhou CJ, Cheng YF, Xie LZ, Hu WL, Chen B, Xu L, et al. Metabolic Syndrome, as Defined Based on Parameters Including Visceral Fat Area, Predicts Complications After Surgery for Rectal Cancer. Obes Surg. 2020 Jan;30(1):319-326. DOI: 10.1007/s11695-019-04163-1.
- Chen X, Zhang W, Sun X, Shi M, Xu L, Cai Y, et al. Metabolic syndrome predicts postoperative complications after gastrectomy in gastric cancer patients: Development of an individualized usable nomogram and rating model. Cancer Med. 2020 Oct;9(19):7116-7124. DOI: 10.1002/cam4.3352.
Publication of the article:
«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 272-282 pages, index UDC 617.55-056.2-092-089:616-008.9-612.015.3